Trametinib (GSK1120212) combined with Pazopanib(Votrient)?


Here is a new study from Japan suggesting Trametinib could help overcome Pazopanib resistance in synovial sarcoma:

Interestingly, a clinical trial with this combination started in 2011 and is still active but not recruiting anymore:

Does anybody have experience with this trial?


The results of this trial were presented at AACR and they look rather disappointing:
It’s not clear whether any synovial sarcoma patient participated in this trial.