Olaratumab with Doxorubicin


Has anybody been on the olaratumab trial?

The results of the phase Ib/II trial were presented at ASCO:


It's not clear whether they had any synovial sarcoma patient on the trial but the results look promising.

The next trial is phase 3 and is not recruiting yet but probably will start soon:



The phase 3 trial started recruiting in 126 locations...


Report from the CTOS meeting on this trial:



A phase 1 trial of olaratumab as monotherapy:


Olaratumab is now getting a new name, Lartruvo and it looks like it will be made available very soon to European soft tissue sarcoma patients:


The FDA just granted accelerated approval to olaratumab which we should call lartruvo:
Has anybody tried this drug?


More information about Olaraumab from Dr. Mark Agulnik can be found here:


This is an option for me if I pick it.


Dr. Brian Van Tine is discussing Olaratumab here:


More details on Olaratumab in the following interview of several oncologists:

They certainly make it sound very promising. I still would like to hear the experience of synovial sarcoma patients…


A few sarcoma experts explain how they decide which patient should get Olaratumab+Doxorubicin in this video:


A few more interesting videos regarding Olaratumab:


I started Olaratumab (Lartruvo) in the beginning of March. My side effects have been next to nothing. I am tired and get a slight headache on days 3 and 4 of my chemo cycles. I have been taking Doxorubicin, but have almost reached my limit. I will have my scans on May 2 to see if the Lartruvo has been helping. So far, I have been very happy with the Lartruvo.


Thanks for sharing Misty!