Synovial Sarcoma Treatments

Synovial Sarcoma Survivors - Online Patient Support Group


Just curious if they have found any links in regards to Synovial Sarcoma and heredity?

Synovial sarcoma is generally not thought as hereditary but some patients may have a predisposition syndrome. The following articles give more details:
Noteworthy, a study published by the International Sarcoma Kindred Study (2nd article) titled “Monogenic and polygenic determinants of sarcoma risk: an international genetic study” mentions an observed association between “germline variants in FANC genes and sarcomas associated with somatic translocations” such as synovial sarcoma.