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Trametinib (GSK1120212) combined with Pazopanib(Votrient)?


#1

Here is a new study from Japan suggesting Trametinib could help overcome Pazopanib resistance in synovial sarcoma:


Interestingly, a clinical trial with this combination started in 2011 and is still active but not recruiting anymore:

Does anybody have experience with this trial?


#2

The results of this trial were presented at AACR and they look rather disappointing:
http://clincancerres.aacrjournals.org/content/early/2017/04/04/1078-0432.CCR-17-0272
It’s not clear whether any synovial sarcoma patient participated in this trial.