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Src Inhibitors


#1

A few years ago, there was a study from Germany suggesting dasatinib as a promising treatment for synovial sarcoma:

http://cancerres.aacrjournals.org/content/73/8/2518.long

A phase 2 trial of dasatinib in advanced sarcoma did not show promising results but it didn't have any patient with synovial sarcoma:

http://meetinglibrary.asco.org/content/41263-74

Has anybody tried one of the following trials:

Dasatinib + ipilimumab (in New York):

https://clinicaltrials.gov/ct2/show/NCT01643278

AZD0424, another Src inhibitor (in the UK):

https://clinicaltrials.gov/ct2/show/NCT01668550