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Synovial sarcoma is a malignant tumor of the soft tissues, usually around joints.
Under the microscope the tumor resembles synovial tissue (the lining tissue of joints). Synovial tissue is found around the tendons (bands of fiber that connect muscle to bone), and can form bursa (fluid filled cushioning pouches or sacs found in spaces between tendons, ligaments and bones) found in the area of joints.
This condition tends to occur in adolescents and young adults and affects more males than females. The most common location of origin is the thigh near the knee, but synovial sarcoma can also occur near other joints, mainly in the arms and legs.
Despite its name, it seldom arises within a joint.
Hi everyone,not sure if this is the place but here comes my question.Some background infoseptember 2011: 15cm tumor in my leg, No metastases and surgeeryBut in 2012 is started ifosfamide/doxorubicine treatement for metastases in the lung. Nearly…Continue
For whoever doesn't know them yet, Adaptimmune is the company that genetically engineered T-cells to target NY-ESO in synovial sarcoma and melanoma. Their trial was initially at NIH and then extended to other locations:…Continue
Hi all. My husband started Votrient last Thursday evening and since has been experiencing painful diarrhea, stomach pains, some hand and foot pain that has not been consistent and tumor site pain. He also has white coat syndrome and it will be very…Continue
Hi - we are looking into going on the trial at Memorial Sloan on the Epizyme EZH2 inhibitor EPZ-6438, Tazemetostat. Has anyone tried this? Can you please share your experience? Thank you. Trish Continue
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